Changes in the Normal Cellular Architecture in the Prostatic Tissue with the Increasing age
Abstract
The frequency of the prostate disorders has been on the increase and disorders such as prostatitis, Benign
Prostatic Hyperplasia and Prostatic Cancer have been on the rise. This study involved 60 cases which were
further subdivided into various age groups. Study was based on the microscopic examination of prostatic
tissue with individual tissues of different age groups. The microscopic examination of prostatic tissue of
different age groups showed that the prostate tissue in contrast to other organs shows hyperplasia instead of
atrophy and that as the age increases there is more proliferation of fibro- musculo glandular tissue producing
increase in the size of prostate which manifests itself in the form of Benign Hyperplasia of Prostate. In
certain Unfortunate conditions there is profound increase in the glandular element progressing to latent
carcinoma of prostate and then to full fledged Carcinoma. A need for urgent readressal to the patient’s
complaints as well as the importance of biopsy and histopathological examination of the tissue is important
in the management of the problem. The histopathological examination can aid the physician/Surgeon to give
the exact details about the possibility of cure, Effective therapy, and staging and most importantly the
prognosis of the patients’ condition. In conclusion, there is change in the normal cellular architecture with
the increasing age in the prostatic tissue.
Prostatic Hyperplasia and Prostatic Cancer have been on the rise. This study involved 60 cases which were
further subdivided into various age groups. Study was based on the microscopic examination of prostatic
tissue with individual tissues of different age groups. The microscopic examination of prostatic tissue of
different age groups showed that the prostate tissue in contrast to other organs shows hyperplasia instead of
atrophy and that as the age increases there is more proliferation of fibro- musculo glandular tissue producing
increase in the size of prostate which manifests itself in the form of Benign Hyperplasia of Prostate. In
certain Unfortunate conditions there is profound increase in the glandular element progressing to latent
carcinoma of prostate and then to full fledged Carcinoma. A need for urgent readressal to the patient’s
complaints as well as the importance of biopsy and histopathological examination of the tissue is important
in the management of the problem. The histopathological examination can aid the physician/Surgeon to give
the exact details about the possibility of cure, Effective therapy, and staging and most importantly the
prognosis of the patients’ condition. In conclusion, there is change in the normal cellular architecture with
the increasing age in the prostatic tissue.
ul-Hassan, A.-., Hassan, G., Shafi, M., & Bhat, M. (2008). Changes in the Normal Cellular Architecture in the Prostatic Tissue with the Increasing age. International Journal of Health Sciences, 2(2). Retrieved from https://pub.qu.edu.sa/index.php/journal/article/view/128
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