Synthesis, characterization, and applications of iron oxide nanoparticles

Authors

  • Abrar Hussain Institute of Integrative Biosciences CECOS University, Peshawar Pakistan
  • Muhammad Yasar
  • Gulzar Ahmad Institute of Integrative Bio-sciences, CECOS University Peshawar, Pakistan
  • Muhammad Ijaz Institute of Integrative Bio-sciences, CECOS University Peshawar, Pakistan
  • Abdul Aziz
  • Muhammad Gharib Nawaz
  • Faraz Ahmad Khan
  • Hamza Iqbal
  • Muhammad Nadeem
  • Dawood Ahmad
  • Farida Anjum Agriculture Research Institute (ARI) Tarnab Peshawar, Pakistan
  • Sulaiman Faisal Institute of Integrative Bio-sciences, CECOS University Peshawar, Pakistan
  • Sidra Usman Institute of Integrative Bio-sciences, CECOS University Peshawar, Pakistan
  • Omar khiam Department of Biotechnology University of Malakand, Pakistan
  • Kalim Ullah Department of Biotechnology University of Malakand, Pakistan

Keywords:

Biocompatibility, Ficus Palmata, Green Synthesis, Microbial Pathogenesis, Nanotechnology, Photo Thermal

Abstract

Objective: The green synthesis method for nanoparticles is getting more attention
globally, due to its lesser cost, non-hazardous, and eco-friendly nature. The novelty
of the present work is to investigate the anti-bacterial and degradation activity of the
green synthesized Iron Oxide NPs.


Methods: In this study, the Iron Oxide NPs were synthesized through a green synthesis
route from leaves of Ficus Palmata. UV-Vis confirmed Iron Oxide NP’s peaks between
(230–290 nm), while Fourier transforms infrared spectroscopy analysis showed that
several groups were involved in reduction and stabilization.


Results: Results indicated that the highest photo thermal activity was shown in
light and it was almost 4 folds greater than the control. Similarly, Iron Oxide NPs
showed excellent antimicrobial potential against bacterial species “Salmonella typhi”
“Xanthomonas Oryzae” and “Lactobacillus” at low concentrations (150 μg/mL).
Hemolytic assay results showed that the toxicity was lesser than 5% at both dark
and light conditions. Moreover, we also evaluated the photo-catalytic potential of
Iron Oxide NPs against methylene orange. Results indicated that almost complete
degradation was noted after 90 min in the presence of continuous light. All tests were
performed in triplicates. All the data was subjected to P-test (P < 0.5) using Excel
and graph pad (V.5.0).


Conclusion: Iron Oxide NPs holds a promising future and could be used in treating
diseases, and microbial pathogenesis and also could be used as a vector in drug delivery.
Moreover, they can also eradicate persistent dyes and could be used as an alternative
to remediate pollutants from the environment.

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Published

2023-07-01

How to Cite

Abrar Hussain, Yasar, M., Gulzar Ahmad, Muhammad Ijaz, Aziz, A., Gharib Nawaz, M., Ahmad Khan, F., Iqbal, H., Muhammad Nadeem, Ahmad, D., Farida Anjum, Sulaiman Faisal, Sidra Usman, Omar khiam, & Kalim Ullah. (2023). Synthesis, characterization, and applications of iron oxide nanoparticles. International Journal of Health Sciences, 17(4), 3–10. Retrieved from https://pub.qu.edu.sa/index.php/journal/article/view/7524

Issue

Vol. 17 No. 4 (2023): Jul-Aug

Section

Original Paper

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