Leucopenia as Presentation of Sarcoidosis
Abstract
Abstract: A 20-year-old male Saudi national presented initially with leucopenia and splenomegaly. The absence of other signs
of disease, progressive pancytopenia and normal bone marrow examination posed a diagnostic dilemma as to the cause of
hypersplenism. Subsequently, the patient had splenectomy the histopathological appearance of which was non-caseating
granuloma. A high level of angiotension converting enzyme (ACE) was found in this patient. Sarcoidosis is a recognized cause
of hypersplenism, and though the disease is not yet widely described in this part of the world. It is the most probable diagnosis in
this patient.
Keywords: Pancytopenia, Splennomegaly, Sarcoidosis.
of disease, progressive pancytopenia and normal bone marrow examination posed a diagnostic dilemma as to the cause of
hypersplenism. Subsequently, the patient had splenectomy the histopathological appearance of which was non-caseating
granuloma. A high level of angiotension converting enzyme (ACE) was found in this patient. Sarcoidosis is a recognized cause
of hypersplenism, and though the disease is not yet widely described in this part of the world. It is the most probable diagnosis in
this patient.
Keywords: Pancytopenia, Splennomegaly, Sarcoidosis.
Akinsanya, L., Hussain, I., Awoniyi, D., & Usman, K. (2008). Leucopenia as Presentation of Sarcoidosis. International Journal of Health Sciences, 2(1). Retrieved from https://pub.qu.edu.sa/index.php/journal/article/view/79
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