Primary cutaneous CD8-positive T-cell lymphoma-granulomatous mycosis fungoides: A rare case report

Authors

  • Sharmila Patil ,Dr. D.Y. Patil Medical College, Hospital and Medical Research Centre, Navi Mumbai, India.
  • Manjyot Gautam
  • Divya Shetty Lokmanya Tilak Municipal Medical College and Hospital
  • Surekha Bhalekar
  • S. Sudhamani

Keywords:

CD 8 positive, granulomatous mycosis fungoides, granulomatous, slack skin, mycosis fungoides

Abstract

Granulomatous mycosis fungoides (GMF) is a rare subtype of T-cell cutaneous lymphoma. Due to the lack of distinct clinical features, GMF may pose a diagnostic challenge, which results in diagnostic delay. The diagnosis is based on histopathological and immunohistochemical findings. Herein, we present an 82-year-old male with itchy lesions over the scalp, face, forearms, trunk, and bilateral lower limbs for 6 months. Histologically, it was a CD8-positive GMF. GMF is a rare subtype of mycosis fungoides with <100 cases in the literature, and most of these cases showed a CD4-positive phenotype. CD8-positive GMF is extremely rare. We observed that it commonly affects elderly females. The patients often present with nodules and do not carry an adverse prognosis.

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Published

2025-03-01

How to Cite

Patil, S., Gautam, M., Shetty, D., Bhalekar, S., & Sudhamani, S. (2025). Primary cutaneous CD8-positive T-cell lymphoma-granulomatous mycosis fungoides: A rare case report. International Journal of Health Sciences, 19(2), 78–81. Retrieved from https://pub.qu.edu.sa/index.php/journal/article/view/8611

Issue

Vol. 19 No. 2 (2025): Mar-Apr

Section

Case report/case series

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