Susceptibility profile of methicillin-resistant Staphylococcus aureus to linezolid in clinical isolates

Authors

  • Ali Shariq College of Medicine,Qassim University.
  • Syed Bilal Tanvir Ziauddin Medical University Queen Mary, University of London
  • Atif Zaman
  • Salman Khan
  • Armeena Anis
  • Misha Aftab Khan
  • Sumaira Ahmed

Keywords:

Linezolid resistant Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, Staphylococcus aureus

Abstract

Objective: To determine the resistance and sensitivity pattern of Methicillin-Resistant Staphylococcus aureus (MRSA) isolates to Linezolid along with its prevalence in a tertiary care hospital of Karachi, Pakistan

Methods and Materials: A Cross sectional study was carried out. This study lasted for about 1 year. Prevalence and sensitivity of linezolid, Vancomycin and Oxacillin was tested against isolates of MRSA.

Results: Out of total 369 specimens 165 were found to be MRSA making the prevalence in our study 44.7% .All of the isolates which were tested positive for MRSA were susceptible to linezolid and no resistance was noted when compared with previous studies performed in Europe and USA.

Conclusion: Stringent implementation of infection control measures along with screening for resistance in patients on prolonged Linezolid therapy or who previously went under linezolid therapy should be performed, coupled with judicious usage of the aforementioned antibiotic should be undertaken, as sufficient data is not available at this point for the clinical spectrum of Linezolid resistant Staphylococcus aureus (LRSA), antimicrobial resistance.

Author Biography

Ali Shariq, College of Medicine,Qassim University.

Assistant Professor,Department of Microbiology,Ziauddin Medical University

Assistant Professor,Department of Microbiology,College of Medicine,Qassim University

Downloads

Published

2017-02-06

How to Cite

Shariq, A., Tanvir, S. B., Zaman, A., Khan, S., Anis, A., Khan, M. A., & Ahmed, S. (2017). Susceptibility profile of methicillin-resistant Staphylococcus aureus to linezolid in clinical isolates. International Journal of Health Sciences, 11(1). Retrieved from https://pub.qu.edu.sa/index.php/journal/article/view/1543

Issue

Vol. 11 No. 1 (2017)

Section

Original Paper

License


Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Most read articles by the same author(s)

1 2 > >>