Uropathogens and their antimicrobial resistance patterns: Relationship with urinary tract infections

Authors

  • Syed Suhail Ahmed Qassim University
  • Ali Shariq
  • Abdulaziz Ajlan Alsalloom
  • Ibrahim H. Babikir
  • Badr N. Alhomoud

Keywords:

Antimicrobial resistance, Escherichia coli, Klebsiella, multidrug resistance, Pseudomonas aeruginosa, qassim, uropathogens, VITEK system

Abstract

Objectives: This study was performed to determine the prevalence of uropathogens causing urinary tract infections (UTIs) and to determine their pattern of antimicrobial resistance.

Methods: This study was conducted on 273 urine samples collected from outpatient departments (OPDs) of Qassim University affiliated hospitals. Fully automated VITEK 2 compact system was used in the identification and antimicrobial susceptibility testing of causative microorganisms.

Results: Of 273 urine samples, only 89 (32.6%) were found to show significant growth for UTI, and overall, drug resistance was found in 92% (n = 82/89) of samples, with most (80%) being resistant to at least two drugs. Antibiotic resistance was commonly observed in ampicillin (88.3%), piperacillin (72.7%), clindamycin (66.7%), amoxicillin/clavulanic acid (66.2%), and trimethoprim/sulfamethoxazole (50%). The commonly isolated microorganisms were Escherichia coli 24 (27%), Klebsiella pneumoniae 11 (12.4%), Proteus mirabilis 4 (4.5%), Pseudomonas aeruginosa 4 (4.5%), Enterobacter cloacae 5 (5.6%), Enterococcus faecalis 5 (5.6%), and Staphylococcus saprophyticus 3 (3.4%).

Conclusions: This research work has shown that patients with UTI in Qassim are at high risk of antibiotic resistance. The work also showed that multidrug-resistant bacteria can lead to momentous therapeutic problems in OPD patients.

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Published

2019-02-14

How to Cite

Ahmed, S. S., Shariq, A., Alsalloom, A. A., Babikir, I. H., & Alhomoud, B. N. (2019). Uropathogens and their antimicrobial resistance patterns: Relationship with urinary tract infections. International Journal of Health Sciences, 13(2). Retrieved from https://pub.qu.edu.sa/index.php/journal/article/view/3666

Issue

Vol. 13 No. 2 (2019): Mar-Apr

Section

Original Paper

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